Research-compound knowledge

Peptide fundamentals

• Peptides are short chains of amino acids joined by peptide bonds; longer chains become proteins.
• Most research peptides are made by solid-phase peptide synthesis (SPPS), then cleaved and purified.
• Key properties on a specification: molecular formula and weight, sequence, salt form and net charge.

Handling & storage

• Peptides usually ship lyophilised (freeze-dried) — the stable, long-shelf-life form.
• Reconstitution is a solution-preparation step, not a dose: a mg → mL → mg/mL calculation only.
• Keep lyophilised vials cold, dry and dark; reconstituted material is far less stable and cold-chain dependent.

Reading a certificate of analysis

• Identity by mass spectrometry (expected vs observed mass) is the meaningful identity check.
• Purity by HPLC should come with the chromatogram, not just a headline percentage.
• The salt form must be stated — it changes the peptide content per milligram.
• A weak CoA has no named lab, no batch reference and a single unsupported number.

The custom sourcing process

• Define the requirement: sequence or compound, grade, purity, salt form, quantity and format.
• We match it to a capable source and gather manufacturer documentation, attributed to source.
• You receive a written quotation with the verified specification before anything is agreed.

Glossary

API

Active pharmaceutical / peptide ingredient — the active compound itself.

CoA

Certificate of Analysis — the document describing a batch’s identity and purity.

HPLC

High-performance liquid chromatography — the standard purity method.

Lyophilised

Freeze-dried; the stable powder form peptides usually ship in.

RUO

Research use only — for laboratory and research use, including in-vivo animal studies; not for use in humans or clinical application.

Salt form

The counterion (e.g. acetate) supplied with the peptide; affects content per mg.